Description & Facts: motel.com Soho, short for "south of Houston Street" and not related to the area in London, is a historic neighborhood in New York City's Lower Manhattan noted for the elaborate cast-iron architecture of many of its buildings, most of which date from the late 19th century. These buildings originally housed warehouses and factories. It is also noted for its cobblestone streets, many of which were eventually repaved with the exception of Crosby Street, Wooster Street, Mercer Street and part of Howard Street. SoHo is located in Lower Manhattan in New York City. It is bounded by Houston Street on the north, Lafayette Street on the east, Canal Street on the south, and Varick Street on the west. There are a number of economy and luxury hotels located nearby. Search on http and MotelGroups.com to find the best lodging at the best rates for you and your family when you visit New York City.